An Analytical Reference Standard
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

4-hydroxy MET

Item No. 11148

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 4-HO MET
  • 4-hydroxy-N-methyl-N-Ethyltryptamine
  • Metocin
Technical Information
Formal Name
3-[2-(ethylmethylamino)ethyl]-1H-indol-4-ol
CAS Number
77872-41-4
Molecular Formula
C13H18N2O
Formula Weight
218.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlEthanol: 0.5 mg/ml
λmax
223, 269, 286, 295 nm
SMILES
CN(CC)CCC1=CNC2=C1C(O)=CC=C2
InChi Code
InChI=1S/C13H18N2O/c1-3-15(2)8-7-10-9-14-11-5-4-6-12(16)13(10)11/h4-6,9,14,16H,3,7-8H2,1-2H3
InChi Key
ORWQBKPSGDRPPA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $62

    Add

    10 mg

    $94

    Add

    25 mg

    $222

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    4-hydroxy MET (Item No. 11148) is an analytical reference standard categorized as a tryptamine.1 4-hydroxy MET is an active metabolite of 4-acetoxy MET (Item No. 18367) that induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential.2,1 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Klein, A.K., Chatha, M., Laskowski, L.J., et al. Investigation of the structure−activity relationships of psilocybin analogues. ACS Pharmacol. Transl. Sci. 4(2), 533-542 (2020).

    2. McIntyre, I.M., Trochta, A., Gary, R.D., et al. A fatality related to two novel hallucinogenic compounds: 4-Methoxyphencyclidine and 4-hydroxy-N-methyl-N-ethyltryptamine. J. Anal. Toxicol. 39(9), 751-755 (2015).

    Product Citations

    Barovic, A., Pittiglio, M.K., Barrett, J.M., et al. Presence of 4‑hydroxy‑N‑methyl‑N‑ethyltryptamine in commercially available products. ACS Omega 11(2), 3448-3454 (2026).

    Kozell, L.B., Eshleman, A.J., Swanson, T.L., et al. Pharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).

    Castleberry, T.A., Lu, B., Smock, S.L., et al. Molecular cloning and functional charcterization of the canine prostaglandin E2 receptor EP4 subtype. Prostaglandins Other Lipid Mediat. 65(4), 167-187 (2001).